Another ILC innovation in the area of flexible containment is the design of the advanced crimping system. This approach replaces the twist-tie-tape and cut method of contained separation of sample sleeves and liners and offers the following benefits:

• Single person operation — increased productivity
• Repeatable, contained separation
• FDA materials
• Support cGMP operations

Specific Key Advantages of the original contained crimp design include:

• Rounded, conformal edges instead of sharp puncture points
• Integral cap provides cover to cut end for added safety
• Third party, independent exposure monitoring to SMEPAC protocols showed nanogram OEL results on a task basis is possible. (Testing performed on production systems using lactose as the surrogate and trained personnel)